Spacing between core recognition motifs determines relative orientation of AraR monomers on bipartite operators
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چکیده
منابع مشابه
Spacing between core recognition motifs determines relative orientation of AraR monomers on bipartite operators
Transcription factors modulate expression primarily through specific recognition of cognate sequences resident in the promoter region of target genes. AraR (Bacillus subtilis) is a repressor of genes involved in L-arabinose metabolism. It binds to eight different operators present in five different promoters with distinct affinities through a DNA binding domain at the N-terminus. The structures...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2012
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gks962